Nutraceuticals
Sanitech Engineers provides customized separation and purification systems for the growing nutraceutical and biotech industries. We have worked with leading biotech companies across different processing applications.
Our solutions support impurity removal, product concentration, oligosaccharide purification, sugar processing, and probiotic biomass recovery. We use membrane filtration, ion exchange, and preparative chromatography based on each process requirement.
We also support manufacturers developing products and facilities that adhere to strict regulations and international standards. Our team supports process development from laboratory trials to commercial-scale production.
Introduction
Nutraceutical processing often involves liquids containing valuable ingredients, solids, salts, sugars, and other impurities. The right separation process helps clarify, purify, and concentrate these valuable ingredients.
Sanitech Engineers provides customized membrane filtration, ion exchange, and preparative chromatography systems. Depending on the application, we use microfiltration, ultrafiltration, nanofiltration, reverse osmosis, and chromatography for separation and purification.
For suitable botanical and natural ingredients, we also provide supercritical CO₂ extraction solutions. Sanitech offers these solutions in collaboration with SFE Process.
Removal of Impurities & Concentration of product
Maintaining the highest level of product purity is crucial in the industrial biotech industry. Sanitech Engineers, a leader in membrane technology, provides state-of-the-art purification solutions. Effective separation is made possible by our top-notch preparative chromatography columns, which remove contaminants and concentrate the intended product.
We meet the specific needs of our esteemed clients with a variety of adaptable Membrane and Preparative Chromatography systems. You can rely on Sanitech Engineers to improve your industrial operations and adhere to strict purity standards while consistently producing outstanding outcomes.
Oligosaccharides Purification
A certain class of oligosaccharides are considered as functional ingredient in food processing. These are considered beneficial for human health and have prebiotic properties. The oligosaccharides are formed by chain of monosaccharides (2-10 linked units) and for industrial scale process for their separation and purification, various techniques are applied.
Solvent extraction, ion exchange, gel filtration, and membrane-based filtration are some the widely used technologies. Each technology has its own pros and cons.
Membrane technology has made its position strong and has become the demanding technology being sophisticated and has multiple cutoff membrane range to selectively filter oligosaccharides. The diafiltration step helps in separating smaller molecules and retains larger oligosaccharides. Non-usage of solvent has made ita green technology of choice
FAQs
Oligosaccharides are purified by removing smaller sugars (monosaccharides), salts, and other low-molecular-weight impurities using membrane filtration (like nanofiltration), adsorption, and chromatographic techniques. These processes help produce concentrated, high-purity oligosaccharide fractions used in nutraceuticals.
Typical methods include nanofiltration, ion exchange, vacuum evaporation, and column chromatography. Membrane filtration, especially NF, offers a green and scalable option for separating larger oligosaccharides from smaller molecules without solvent use.
Oligosaccharides consist of short chains of sugar units (usually 3–10 monosaccharides) and often serve as prebiotic ingredients, supporting gut health. In contrast, simple sugars such as glucose and fructose are single-unit monosaccharides mainly used for energy.
Sugar
Learn about the revolutionary potential of the ion exchange technique for sugar syrup colour removal. The ideal medium is our state-of-the-art ion exchange resin, which selectively preserves colour on the syrup’s beads while decolorizing the syrup. Accept improved quality as we eliminate undesirable colours, enhancing your product’s flavour and look. Additionally, our cutting-edge Nanofiltration method offers an extra way to decolorize sugar syrup with remarkable outcomes. With our cutting-edge technologies, which are designed to take your sugar production to new heights of excellence, you may experience the ideal fusion of science and sweetnes
FAQs
Brown color in sugar syrups is removed using decolorization techniques such as activated carbon adsorption or ion exchange resins. These capture color-causing compounds and clarify the product without significantly affecting sugar composition.
Color removal is typically carried out using ion exchange resin systems, mixed-bed resin columns, or activated carbon filtration units designed to trap and remove colored impurities from sugar syrups.
Starch derivatives
Learn about the many uses of starch derivatives in the beverage, culinary, and medicinal industries. We transform the production process by utilising the most recent developments in Ion Exchange and Nanofiltration technology. Since the world is looking after sustainable and eco-friendly processes, our state-of-the-art systems guarantee outstanding global quality. Our green technology can be used as an alternative to traditional thermal methods.
FAQs
Starch derivatives are functional carbohydrates produced from starch that include glucose syrups, maltodextrins, fructose, dextrins, and modified starches. These serve as sweeteners, texturizers, or carriers in food, beverage, and nutraceutical applications.
In pharmaceuticals, starch is used as an excipient (binder and disintegrant) and as a source for sugars like glucose. In nutraceuticals, starch derivatives act as functional ingredients—providing texture, energy, or delivery systems for active compounds.
Glucose, fructose separation/purification
With our Microfiltration and Ion Exchange separation technologies, discover the revolutionary transformation in biomass-based extraction from fermentation broth. These cutting-edge techniques ensure better outcomes by replacing conventional rotary hoover and pressure filters. Ultrafiltration effectively blocks complex molecules with larger molecular weights while allowing for selective salt flow. Use nanofiltration to its full potential for applications that call for moderate inorganic removal and high organic removal.
As we set the standard for creative solutions, see increased purity and efficiency in your operations. Bid farewell to antiquated techniques and welcome the purification and separation of the future. Come along as we use our cutting-edge membrane and ion exchange technologies to alter industries.
FAQs
Fructose and glucose are separated using chromatographic techniques like ion-exchange or ligand-exchange chromatography, which exploit differences in molecule-resin interactions to collect each sugar at high purity.
Chromatographic separation involves passing a mixed sugar solution through a resin bed where each sugar binds differently. This causes them to elute at separate times and be collected as distinct fractions.
Yes — classic tests like Benedict’s or Barfoed’s test can differentiate reducing sugars. However, industrial scale separation commonly relies on chromatography and modern analytical techniques for specificity. (General analytical principle)
Probiotic Biomass Separation from Fermentation Broth
At Sanitech Engineers, find innovative answers to the food industry’s increasing need for premium probiotics. The ideal way to effectively separate probiotic biomass from the fermentation broth is with our cutting-edge Microfiltration equipment. Our technology, which prioritises accuracy and efficacy, guarantees that you get the best probiotics for your goods.
Our cutting-edge biomass recovery process, created to address the growing significance of probiotics in the rapidly changing food market of today, can help you stay ahead of the competition. You can rely on Sanitech Engineers to provide dependable and cutting-edge solutions that will maximise your probiotic output.
FAQs
Probiotics are beneficial live microorganisms that support gut health, aid digestion, and boost immune function. They are widely used as nutraceutical supplements to improve overall wellness. This aligns with the increasing demand for fermented probiotic products.
Probiotics are produced by cultivating specific beneficial bacterial strains under controlled fermentation, then harvesting and concentrating the biomass. Downstream separation technologies like microfiltration are used to recover and concentrate probiotic cells from fermentation broth.
Nutraceutical Processing Technologies
Microfiltration (MF)
Used for clarification and removal of suspended solids, microbial biomass and larger particles from suitable process streams.
Probiotic biomass separation
Fermentation broth clarification
Pre-filtration
Liquid clarification
Ultrafiltration (UF)
Used to retain and concentrate larger molecules while allowing smaller dissolved components to pass through, depending on membrane cut-off.
Macromolecule concentration
Protein-rich ingredient processing
Clarification and concentration
Process-stream purification
Nanofiltration (NF)
Provides tighter membrane separation and can be used for selective concentration, desalting and separation of suitable low-molecular-weight components.
Oligosaccharide purification
Sugar-stream purification
Selective concentration
Removal of smaller impurities
Nanofiltration (NF)
Provides tighter membrane separation and can be used for selective concentration, desalting and separation of suitable low-molecular-weight components.
Oligosaccharide purification
Sugar-stream purification
Selective concentration
Removal of smaller impurities
Reverse Osmosis (RO)
Provides high-selectivity separation for water and dissolved components and can support suitable concentration or water-related process applications.
Process-water applications
Concentration of suitable streams
Dissolved-solute separation
Ion Exchange
Uses selective resin interactions to remove or separate charged components and can support demineralisation, decolourisation and specific sugar-processing applications.
Sugar syrup decolourisation
Demineralisation
Ion removal
Application-specific sugar processing
Preparative Chromatography
Provides selective separation where target ingredients and closely related components require higher-resolution purification.
Functional ingredient purification
Sugar separation
Application-specific high-purity fractions
Supercritical CO₂ Extraction
Uses carbon dioxide under supercritical conditions to extract suitable compounds from botanical and natural raw materials with reduced reliance on conventional organic solvents.
Botanical extracts
Essential oils
Selected bioactive compounds
Natural ingredient processing
Technology Selection Table
Technology | Primary Role | Typical Nutraceutical Applications |
| Microfiltration | Clarification / biomass removal | Probiotics, fermentation broth, suspended-solids removal |
| Ultrafiltration | Macromolecule retention / concentration | Protein-rich streams, concentration, purification |
| Nanofiltration | Selective low-MW separation / concentration | Oligosaccharides, sugar streams, desalting |
| Reverse Osmosis | High-selectivity dissolved-solute separation | Process water and suitable concentration applications |
| Ion Exchange | Selective ionic separation | Decolourisation, demineralisation, sugar processing |
| Preparative Chromatography | High-resolution separation | Functional ingredients and sugar separation |
| Supercritical CO₂ Extraction | Selective extraction from suitable natural materials | Botanical extracts, essential oils and bioactives |
Nutraceutical Applications We Support
- Impurity removal and product concentration
- Oligosaccharide purification
- Sugar syrup clarification and decolourisation
- Starch-derivative processing
- Glucose and fructose separation / purification
- Probiotic biomass recovery
- Fermentation broth clarification
- Functional ingredient purification
-
Botanical and natural ingredient
extraction
- Process-water and concentration applications
- Laboratory and pilot process development
From Lab Trials to Commercial Production
Process Development & Scale-Up for Nutraceutical Applications
Nutraceutical separation processes often need laboratory or pilot evaluation before commercial equipment is finalized. Feed composition, membrane selection, operating pressure, flux, concentration factor, resin selection and product recovery can influence the final process design.
Sanitech Engineers supports process development and system engineering from proof-of-concept and pilot work through commercial-scale implementation.
Process Evaluation → Lab / Pilot Trials → Optimization → Scale-Up → Detailed Engineering → Manufacturing → Automation → Installation & Commissioning
Customized Nutraceutical Processing Systems
Each nutraceutical ingredient has different physical and chemical characteristics. Sanitech Engineers develops systems around the specific product, process stream and production objective rather than relying only on a standard equipment configuration.
- Feed composition and solids loading
- Target ingredient and impurity profile
- Membrane type, pore size or molecular-weight cut-off
- Membrane area and operating pressure
- Resin / chromatography selection where applicable
- Temperature-sensitive product requirements
- Lab, pilot and commercial scale
- Instrumentation and automation
- Materials of construction
- Cleaning requirements
- Process volume and target concentration
Why Sanitech Engineers?
30+ Years of Process Engineering Experience
Experience in membrane filtration, separation and purification technologies across process industries.
Multiple Separation Technologies
Membrane filtration, ion exchange, preparative chromatography and Supercritical CO₂ solutions allow the process route to be selected around the application.
Process Development Support
Laboratory and pilot work can support technology evaluation and scale-up before commercial implementation.
Customized System Design
Systems are engineered around feed characteristics, target product, required separation and production scale.
Integrated Engineering Support
Capabilities can include process development, detailed engineering, fabrication, automation, installation and commissioning.
Lab-to-Commercial Scale-Up
Support from proof-of-concept and pilot requirements through commercial-scale equipment.
FAQs
Removing impurities is the process of eliminating unwanted substances—such as salts, color bodies, suspended solids, small molecules, or contaminants—from a formulation to improve product purity, safety, and quality prior to concentration or further processing.
Key methods include advanced membrane filtration technologies (microfiltration, ultrafiltration, nanofiltration, reverse osmosis) and chromatographic separation techniques. These processes separate target molecules from undesired components based on size, charge, or physical properties to deliver high-purity nutraceutical products.
Extraction techniques for natural bioactive ingredients include solvent extraction, membrane separation processes, adsorption, and chromatography. These methods isolate targeted bioactive compounds from plant or biological sources for use in nutraceutical formulations.
Membrane filtration uses selective membranes to separate components in a liquid process stream according to factors such as particle size, molecular size and membrane characteristics. In nutraceutical processing, it can support clarification, purification, concentration and biomass separation.
Microfiltration, ultrafiltration, nanofiltration and reverse osmosis can be used for different nutraceutical applications. The appropriate technology depends on the feed, target ingredient, impurity profile and required separation.
Impurities may be reduced using clarification, membrane filtration, ion exchange, adsorption or chromatography. The process is selected according to the type of impurity and the properties of the target ingredient.
Oligosaccharide purification can involve nanofiltration, diafiltration, ion exchange and chromatography. Suitable membrane processes can help reduce monosaccharides, salts and other smaller components while retaining the desired oligosaccharide fraction.
Nanofiltration offers selective separation of suitable low-molecular-weight components and can be evaluated for concentrating oligosaccharides while reducing smaller sugars or salts. Performance depends on membrane characteristics and feed composition.
Sugar syrup decolourisation can use technologies such as ion exchange or adsorption to reduce colour-causing components. Nanofiltration may also be evaluated for suitable sugar purification processes depending on the feed and desired product specification.
Glucose and fructose can be separated using selective chromatographic processes that exploit differences in their interactions with the stationary phase. The system configuration depends on feed composition, purity targets and production scale.
Microfiltration can be used for suitable probiotic fermentation streams to retain microbial cells while allowing smaller liquid-phase components to pass through. Operating conditions and membrane selection are chosen according to the microorganism and process requirements.
Ultrafiltration can retain and concentrate larger molecules while allowing smaller dissolved components to pass through. It can support concentration and purification of suitable protein-rich or macromolecular nutraceutical streams.
For suitable applications, membrane concentration can reduce the amount of water that must be removed by thermal methods. The actual process benefit depends on the product, concentration target and overall process design.
Supercritical CO₂ extraction can be used for suitable botanical and natural materials to recover selected compounds such as oils and other bioactive fractions. Process conditions are adjusted according to the raw material and target compounds.
Yes. Systems can be customized according to feed composition, target ingredient, membrane or resin requirements, operating conditions, process volume, automation needs and production scale.
Sanitech Engineers supports process development and system engineering from laboratory or pilot evaluation through commercial-scale implementation, depending on project requirements.
Technology selection should consider the target ingredient, impurity profile, molecular size, solids content, temperature sensitivity, desired purity, concentration target, throughput and process economics. Laboratory or pilot trials may be useful before scale-up.
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