How High-Pressure DAC Columns Improve HPLC Performance
Modern labs have a problem that never goes away: how to clean up vast amounts of compounds without losing quality or speed. It can be hard for traditional preparative HPLC systems to find this balance, which leads to uneven results and the need to replace columns repeatedly. The answer is to learn how managing pressure […]
Membrane Filter Techniques Used in Tangential Flow Filtration
Bioprocessing professionals know how disappointing it is when a potential therapeutic protein loses potency during purification. Membrane ultrafiltration has to be used with utmost care. Tangential flow filtration membrane selection isn’t merely a technical issue; it can mean success or economic loss. What is Tangential Flow Filtration? TFF changes biomolecule separation and cleaning. Standard dead-end […]
Beyond the Hardware: Why Peptide Downstream Processing Requires a Trusted Partner
Peptide therapies is a rapidly developing field with great potential, but successful downstream processing (DSP) is essential to bringing new peptides from discovery to commercialisation. Although the mainstays of peptide purification are advanced membrane filtering and preparative chromatography methods, the apparatus is but one component of the whole process. The choice of a reliable equipment […]
Tackling Peptide Processing Hurdles with Advanced Separation and Purification Technologies
The advancement in science and technology has increased the life span of an individual. Therapeutics which is a branch of medicine has also advanced towards prevention and treatment of an individual finally alleviating the disease. Since, majority of disease-causing microbes have become resistance to drugs, there is a need of a biomolecule which can be […]
Choosing the Right Membrane for Lab-Scale Applications
Choosing a membrane with proper material of construction (MOC), size of pores (cut off), and configuration (spiral or tubular) is the first step to getting accurate laboratory filtration results. We can easily differentiate between the clean and dirty (high solids load) samples just by visual observations and then choosing the correct membrane. You will get […]
What is Peptide Processing and How is it Enhanced by NF, IBD & DAC Chromatography columns?
Introduction To make, purify, and get peptides ready for use in pharmaceuticals, nutraceuticals, and diagnostics, peptide processing comprises complex industrial stages. These sequences of amino acids (2 to 50 residues) are now very useful for treating cancer, hormones, infections, and metabolic disorders. By 2027, the worldwide peptide therapeutics industry is expected to be worth more […]
The Role of Caustic Soda Recovery in Sustainable Plant Operation
NaOH or caustic soda has a wide application in various industries, including textiles, pharma, dairy, and food processing. In production systems, it is used from cleaning-in-place (CIP) systems to fabric treatment showers. This is done for sanitation and production quality control. However, this process yields large amounts of waste and expenses. At this point in […]
What is whey?
Whey is a by-product of the Dairy industry yielded from cheese production. For many years, whey was considered insignificant and was disposed of as waste. In some cases, they are used as animal feed. Whey is one of the two proteins in milk (the other being casein). In their original form, the two milk proteins […]
Inline Buffer Conditioning (ILBC)
The preparation of a large number of buffers is becoming a challenge for the biopharmaceutical industry since buffer solutions are required in large quantities and within a short interval of time. It is also a critical operation as it has to be very specific in terms of concentration to get a high yield. Traditionally buffer […]
A Simple Guide to Caustic Recovery Systems
We are living in a highly industrialized world today. As we are enjoying its benefits, the responsibility of safeguarding the environment also increases. Recycling or recovery of useful chemicals from waste is one of the primary ways to achieve the valuable chemicals and simultaneously protect the environment from pollution, and that’s where the Caustic recovery […]